Creatine is an organic compound that is found in vertebrates, where it facilitates the recycling of adenosine triphosphate (ATP), primarily in muscle and brain tissue. It is an amino acid that is located mostly in the bodys muscles as well as in the brain. Creatine is involved in making energy for muscles, and about 95% of it is found in skeletal muscle. It helps create a steady supply of energy in your muscles so they can keep working, especially while you’re exercising. Creatine is also a natural source of energy that helps your skeletal muscles flex (contract) . About half of your body’s supply of creatine comes from your diet, especially protein-rich foods such as red meat and seafood. The other half is produced naturally in your liver, kidneys, and pancreas. Creatine supplements are popular among bodybuilders and competitive athletes, and they are estimated to spend roughly $14 million per year on creatine supplements. The attraction of creatine is that it may increase lean muscle mass and enhance athletic performance, particularly during high-intensity, short-duration sports. However, not all human studies show that creatine improves athletic performance, nor does every person seem to respond the same way to creatine supplements.