what is hyperuricemia

11 months ago 26
Nature

Hyperuricemia is a medical condition characterized by high levels of uric acid in the blood. Uric acid is a waste product that is created when the body breaks down purines, which are chemical compounds found in certain foods and drinks. Normally, uric acid dissolves in the blood, passes through the kidneys, and leaves the body in urine. However, if too much uric acid stays in the body, it can lead to the formation of sharp crystals that can settle in the joints and cause gout, a painful form of arthritis, or build up in the kidneys and form kidney stones. Hyperuricemia can occur due to increased production of uric acid, decreased excretion of uric acid, or a combination of both processes. The normal upper limit for uric acid in the blood is 6.8mg/dL, and anything over 7 mg/dL is considered saturated, and symptoms can occur. However, most people with hyperuricemia have no symptoms and don’t require long-term therapy. The most common manifestation of hyperuricemia is gout, which can be very painful and is easily treatable. Other symptoms associated with hyperuricemia include uric acid nephrolithiasis, which can cause flank pain, hematuria, nausea/vomiting, and colicky pain. Hyperuricemia can be treated by changing some aspects of daily routine, such as tweaking the diet or drinking more water, or by taking medication to lower uric acid levels or treat any symptoms.