what is mg

Myasthenia gravis (MG) is a chronic autoimmune disorder that affects the communication between nerves and muscles, resulting in weakness of the voluntary muscles. It is characterized by muscle weakness and fatigue of varying severity, affecting muscles in the eyes, face, neck, and limbs. MG is caused by antibodies that block, alter, or destroy the communication point between the nerve and muscle, known as the "neuromuscular junction". The primary symptoms of MG include droopy eyelids, double or blurred vision, weak arms, hands, neck, face, or legs, as well as excessive fatigue. In severe cases, MG can lead to difficulty in chewing, smiling, swallowing, talking, or breathing. The condition is considered a lifelong neuromuscular disease, and while there is no cure, treatments are available to help manage the symptoms. These treatments may include immunosuppressive drugs, which can improve muscle strength by suppressing the production of abnormal antibodies. Additionally, some patients may achieve remission with the help of these treatments. The onset of MG is suspected to be triggered by a combination of factors, such as an abnormal thymus gland, genetic predisposition, and an illness or event that stimulates the immune system.