Sore nipples to touch can be caused by several common reasons including friction from clothing or bras, hormonal changes, infections, breastfeeding issues, skin conditions like eczema or dermatitis, and even more serious concerns like breast cancer. Hormonal fluctuations during menstruation, pregnancy, or breastfeeding often cause nipple tenderness. Physical irritation from friction during exercise or wearing ill-fitting clothes is another frequent cause. Infections or skin allergies may also lead to soreness and inflammation. If the soreness persists, worsens, or is accompanied by other symptoms like lumps or nipple changes, a healthcare professional should be consulted for accurate diagnosis and treatment.