how many mg of acetaminophen can i take at once

The maximum amount of acetaminophen that can be taken at once by a healthy adult is generally 1,000 mg per dose. This dose can be taken every 4 to 6 hours, but one should not exceed 4,000 mg in a 24-hour period to avoid risk of liver damage. Extended-release forms may have a different dosing interval and maximum dose (e.g., 650 mg every 8 hours, with a max of about 3,900 mg daily). It is important not to exceed the recommended dose on the packaging and to consider all medications being taken that might contain acetaminophen to avoid overdose. For safety, lower daily limits may be advised for people with liver issues or those drinking alcohol regularly.