It is generally not safe to drink alcohol while taking DayQuil or within several hours after taking it. Mixing DayQuil and alcohol can cause heightened side effects such as dizziness, drowsiness, nausea, and impaired coordination. More serious risks include liver damage, stomach bleeding, respiratory depression, seizures, and even unconsciousness. DayQuil contains acetaminophen, which combined with alcohol increases the risk of liver toxicity. The active ingredient dextromethorphan in DayQuil may also increase sedation when mixed with alcohol. Most sources recommend waiting at least 4 to 6 hours after taking DayQuil before consuming any alcohol, and even then, alcohol intake should be moderate and cautious. It is safest to avoid alcohol entirely while sick and using the medication, or to consult a healthcare professional for personal guidance if alcohol consumption is necessary during treatment.
